Comet Lesions in Patients with Pseudoxanthoma Elasticum.

Turk J Ophthalmol. 2015 Dec;45(6):268-270

Authors: Tatl?p?nar S, ?ahan B, Altunsoy M

Abstract
Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch's membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d'orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions.

PMID: 27800246 [PubMed - in process]